First - Unless you have aftermarket airbags on the rear axle you will likely end up towing nose high with those soft f150 leaf springs, blinding other drivers with your headlights
(youíll need to readjust you front lights but thatís a bandaid to the issue)
Second - unless you also drop the front differential to correct front axle angle plan to potentially plow through CV boots and half shafts at an accelerated rate.
Third - Weight distribution will also be very important to get dialed in just right as well, as always, to re-load the front suspension as much as possible. That being said it can be difficult to throw a lot of weight forward on a relatively long wheelbase f150.
Finally.... check the clearance of your upper control arms and check your shock length. If you keep the factory control arms and shock length - you could very well bottom them out when towing down the road and hit an undulating area on the highway at speed, flexing the suspension up and down in the front. Metal on metal under dynamic load is never a good thing at 60 mph, especially when it involves failure of the front shocks because they are too short
Not sure if that helps or not... Iím actually installing 2Ē level kit on my gmc 2500 this weekend including new upper control arms and diff spacers. I have rear airbags already to increase spring rate and will still carry a 1Ē rake front to back so Iíll be level towing when WD is fully applied. (Today I tow full loaded, wet and ready for camping with a 2Ē rake)
2Ē level on these trucks is negligible from a COG perspective - your already sitting tall. Not sure if you are adding spacers or new coils but if the latter you will notice driving dynamics change some, likely, which could be positive or negative depending on the before / after spring rates. Same goes for shocks / struts.