If you are entering the BRP from the Asheville area, probably your biggest challenge will be getting around the road closure north of Asheville near Mt. Mitchell. It is a long term closure because the road literally fell off the mountain. Be sure to check out the road closure link at
Real-time Road Closures | Blue Ridge Parkway before your trip so you can plan your detour. Many of the roads in the area are incredibly twisty and you don't want to end up like this guy
https://youtu.be/icXipapYSmg
Enjoy your trip! The scenery is a national treasure.