I had a 2010 Airstream 28ft Flying Cloud that was problem free from the start. Then I upgraded to my current Airstream when I retired and went full timing. It took two years to work the bugs out with trips to the Airstream Service Center every six months as I was moving around. I'm no longer full timing but I've incurred some major maintenance expense in the past year and a half that probably relate in part to using the trailer full time for three and half years.
In my opinion, Dometic air conditioners and refrigerators don't hold up. I've replaced both front and back AC units and the refrigerator. Also be sure to have the trailer's wheel hubs inspected and serviced as needed. Don't ignore them like I did. I make an annual trip to the Airstream Service Center for maintenance, which is just the cost of owning a home that travels on our nation's bumpy highways and byways.