Center location of the batteries makes leveling the load from side to side easier, but I would suggest you also look at the weight of other components such as frig, water, heater furnace (any heavy item mounted on the side of the trailer) and see what effect they have. You don't have as much leeway in placing appliances as you do the batteries. Also keep in mind that placing 4 batteries at the front may increase your tongue weight more than desired. This may seem like over kill, but I think its important to balance the load. Not only, to maintain proper tongue weight, but also from side to side.
Regarding your wiring, keep in mind that gauge not only depends on load of the item but also the length of your circuit and voltage drop loss %. Look up all the manufacturers specs and length of your circuit to make sure 12 gauge is adequate. Charts are readily available to assist in determine wire gauge. Here's one from a marine manufacturer that I use.
https://www.bluesea.com/resources/1437
Also your connections between each battery and from the batteries to your electrical panel requires a lot larger gauge. There are some great pros on the forum that will keep you on track (I am not one of them, just a novice trying to learn what I can from them).