To pressurize the black and gray tanks you would have to seal the roof vents and all the plumbing drains. The fresh water tank has a vent that would have to be plugged. The plastic tanks aren't meant to be pressurized so even if you got everything sealed you wouldn't be able to use very much pressure and it wouldn't be much of a test with out some very accurate gauges. I would fill them with water and start looking for leaks.
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