the systems will be similiar to you sailboat, just having a chassis underneath all that will be you biggest change. Airstream motorhomes come in so many varieties its hard to nail down common problems without know what year range, price range etc you are looking at,
You can also visit RV.et and other such ocmmunities to get more specific info on motorhomes in general, as opposed to just the AS brand.
So many variables. Diesel or gas, new or old, class A, B, C, etc.
You need to get familiar with the terminology and figure out what appeals to you. There are some terrific newer ones out there.