Argosy/Shuttle Bus Redo

[snowy23]

Hey ya'll. Been a while away from the site, but back with a passion!! Currently working on replacing the floor in my 77 24' mh. Looking at my past posts, (search snowy23), you will know I bought a 77 shuttle bus that was revamped into a mh. (I found that out after the fact). Anyway, I started tearing into the bed area and found rotted flooring and the more I saw, the more I tore out!! Now the whole insides are out with the exception of the refrigerator/microwave cabinet. I'm about to replace all the flooring after I treat the floor support framing with por 15 among other stuff. My question is will removing the screws that run along the c channel down into the plywood sacrifice any integrity in the frame or body structure? I feel like cutting them off will definitely make the plywood easier to install without having to do much cutting. Just don't want to cut the screws if it means weakening the overall body structure.
Thanks for any help!!