"Disrepair" is a bit of an understatement as the road has been in dreadful condition for many years, especially the right hand lane.
From the Oregon line to I-505, the road is much improved, some construction spots, but the repairs appear to be of good quality, unlike the more southern segments.
I can't speak to the I-505 to Tracy segment.
From Tracy to Buttonwillow there have been repairs, largely cosmetic. They applied a "slurry" a couple of years or so ago to some stretches, but it did nothing to cure the underlying defects, and only made them more difficult to spot while driving normal speeds as it gave the illusion of nice, new pavement. Not so. The transitions at underpasses are generally awful. No matter what they did to the highway, they did nothing to the broken concrete of the underpasses and the abrupt transition from road surface to underpass concrete. There are segments where the road is fairly decent, allowing you to travel in relative comfort. The segment between Tracy and Coalinga is decent as I recall. There are other segments between Coalinga and Lost Hills and that are awful, inspiring me to travel in the left lane.
I haven't traveled the section from Lost Hills to Buttonwillow is a couple of years, but that used to be one of the worst. Perhaps they've done something, dunno. I-5 does not technically go to Bakersfield, but rather just south of Bakersfield. I usually prefer not to take Highway 58 between I-5 and Bakersfield, as I prefer a different route when traveling through Bakersfield...in part due to road condition.
I haven't traveled the section between Buttonwillow and the Grapevine with the Airstream recently enough to give an accurate report.
I hope this helps, and be sure to secure your trailer contents, drawers, and overhead cabinets well.