We have a 30' with a slide and I had 3 flats with the standard 15" ST tires, mostly Goodyear Marathons. I switched, like many, to a 16" rim and Michelin LT E rated tires. I also added the Centramatic auto balancers both to our AS and TV. Never another issue with tires. Only safe way to go IMHO.
2008 F-250 4X4 Lariat V-10
2002 Airstream Classic 30' w/SO #2074
2007 Kubota 900 RTV
1996 Ford Bronco
2007 Lincoln LT