After experiencing a GYM blowout this past May, in the course of the repair at JC I had them change my wheels to the 16" ones with Michelin LTX 225/75R16(E) tires. We just got back from a 1-week 1,000 mile trip. As part of this upgrade we also installed with the Centramatics (both on the AS and the TV). The ride was smooth and the tires ran cool at 60mph - previously, with 15" ST tires, the tires ran warm, mainly because ST tires are speed-rated. See Centramatic Wheel Balancer, Tire Balancers for DFW Trucks
I should add that we tow about 15,000 miles per year.