How much of the floor needs replacing? If better than 40-50%, then probably less hassle to do a shell off then trying to patch it in. You'll get a better job with a shell off as well and have better access to the frame to repair and preserve it. It's not that I'm recommending a shell off, but at some point it does make more sense than the alternative.
Yes it can be done, I did it after removing lower inside panels and belly pan .We were able to do ends first then flair the sides to fit the middle sheets .With good results. Good luck
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